John Elfar | Orthopaedics and Rehabilitation

Our lab has found striking new properties of Erythropoietin and 4-aminopyridine in the regeneration of nerve and preservation of muscle after peripheral nerve trauma. Our published work shows these compounds seem to enhance myelination at the site of severe nerve crush injuries and alter the evolution of post-denervation muscle atrophy - key unsolved problems in orthopaedic trauma. We seek collaborations to solve key problems in the treatment of these patients, including diagnosis of severed nerves, treatments of nerve degeneration, and muscle atrophy.