Neuron movements caused by push, pull of motor proteins, study finds

image showing motor proteins moved along a microtubule using single-molecule fluorescence microscopy

By Mariah R. Lucas

UNIVERSITY PARK, Pa. — Neurons, which are responsible for producing the signals that ultimately trigger an action like talking or moving a muscle, are built and maintained by classes of motor proteins that transport molecular cargo along elongated tracks called microtubules. A Penn State-led team of researchers uncovered how two main groups of motor proteins compete to transport cargo in opposite directions between the cell body and the synapse in neurons.  

Andrew Read

Andrew Read

Director, Huck Institutes of the Life Sciences
Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology

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Spencer Szczesny

Spencer Szczesny

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William Pierce

William Pierce

Evan Pugh University Professor Emeritus of Surgery

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Yuguo Lei

Yuguo Lei

Associate Professor of Biomedical Engineering Faculty Director, Sartorius Cell Culture Facility, Huck Institutes of Life Sciences

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Susan Hafenstein

Susan Hafenstein

Associate Professor of Medicine, Biochemistry and Molecular Biology, Microbiology and Immunology

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James Connor

James Connor

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Peter Butler

Peter Butler

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Reka Albert

Reka Albert

Distinguished Professor of Physics & Biology

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