The distinction between conventional electronics and soft human body and organs poses a grand challenge in the broad medical field. Our solution to address the challenge is to invent a new class of electronics, namely rubbery electronics, which is constructed from elastic rubber electronic materials with tissue-like softness and mechanical stretchability to allow seamless integration with soft deformable tissues and organs. This presentation will discuss some recent development and understanding of rubbery organic semiconductors, rubbery transistors, integrated electronics, sensors and bioelectronics.