Supramolecular chemistry is a strategy to engineer materials through directional noncovalent interactions (e.g., hydrogen bonds, host-guest interactions, metal coordination). Despite the dynamic and reversible nature of supramolecular interactions, their full integration into synthetic materials design platforms is sluggish. Nature, however, fabricates some of the most beautiful 1D, 2D, and 3D self-assembled architectures using a combined array of complex synthetic techniques and exploitation of noncovalent chemistry. So the question arises… why can’t we do the same to control molecular architecture?

Elizabeth Elacqua