The molecules of life, proteins and nucleic acids are essential parts of every living organism and participate in most processes within cells. Many proteins and some RNA are enzymes that catalyze a number of biochemical reactions. These macromolecules purified from different research labs across Penn State have been studied using a variety of biophysical techniques in our facility. The methods we employ include X-ray crystallography, solution small angle X-ray scattering (SAXS), dynamic light scattering, bio-layer interferometry, circular dichroism spectroscopy, micro electron diffraction, molecular modeling, isothermal calorimetry and differential scanning calorimetry. Come learn about some recent examples where the facility has assisted researchers in delineating the structure-function enigmas of various macromolecules.

Neela Yennawar | Huck Institutes of the Life Sciences