While most researchers are familiar with standard “macro” FTIR, Raman, and UV-Vis.  It is less known that the MCL currently maintains instrumentation capable of acquiring high spatial resolution data for all of the aforementioned molecular spectroscopy techniques.  This talk will discuss the applications of AFM-IR (Nano-IR), Micro-FT-IR and Micro-UV-Vis while highlighting the limitations of each techniques as it relates to sample preparation requirements and common artifacts.