Sebastiaan Van Nuffel

Sebastiaan Van Nuffel



Sebastiaan joined the MCL in 2019 as a postdoctoral scholar. Throughout the years, he has built up an extensive expertise in imaging mass spectrometry, specifically ToF-SIMS, and many complementary surface science techniques. He has performed both applied and fundamental research and worked with a wide variety of samples ranging from plastics to biological applications and even cultural heritage. His current research interests revolve around biological ToF-SIMS research and hyperspectral image data analysis using advanced multivariate analysis tools.


  • Data acquisition and processing using ToF-SIMS, MALDI, XPS, electron microscopy, FTIR spectroscopy, AFM, interferometry and spectroscopic ellipsometry
  • Chemometrics (incl. multivariate analysis) for advanced data analysis
  • MATLAB programming
  • Primary cell culture, tissue processing and sectioning, and optical microscopy
  • Cleanroom processing and photolithography

Selected Publications



N-017 Millennium Science Complex
University Park, PA 16802

Telephone: +1-814-865-9595